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May 28, 2010 · PDZ domains are abundant protein interaction modules that often recognize short amino acid motifs at the C-termini of target proteins.
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Because binding specificities are based on a few amino acid residues, these domains are uniquely suited to permit evolution of new protein interactions by ...
Jun 28, 2018 · PDZ domain proteins are involved in a variety of signal transduction pathways. (A) PDZ domains interact with neuronal receptor proteins. A ...
The PDZ domain is a common structural domain of 80-90 amino-acids found in the signaling proteins of bacteria, yeast, plants, viruses and animals.
Nov 6, 2018 · The scaffolding protein PDZK1 has been associated with the regulation of membrane transporters. It contains four conserved PDZ domains, which ...
We have determined the crystal structure of the N‐terminal PDZ domain of InaD bound to a peptide corresponding to the C‐terminus of NorpA to 1.8 Å resolution.
PDZ domains typically bind peptides located at the extreme C-terminus of target proteins, engaging the terminal carboxylate moiety with backbone amide groups ...
The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling.
Sep 13, 2018 · The scaffolding protein PDZK1 has been associated with the regulation of membrane transporters. It con- tains four conserved PDZ domains, ...
Sep 15, 2001 · PDZ domains are protein-protein recognition modules that play a central role in organizing diverse cell signaling assemblies.